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Peptide Hormone

Search Result - 1

HMRbase accession number	10910
Swiss-prot Accession number	P01325 (Sequence in FASTA format)
Description	Insulin-1 precursor [Contains: Insulin-1 B chain; Insulin-1 A chain].
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length	108 Amino acids
Molecular weight	12160
References	1  PubMed abstract 3104603 2  PubMed abstract 2397023 3  PubMed abstract 16141072 4  PubMed abstract 5063718
Domain Name	Insulin
Hormone Name	Insulin-1 A chain
Mature Hormone Sequence	GIVDQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein	21 Residues from position (88-108)
Receptor	N/A
Gene ID	16333
PDB ID	1L6Q
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	11339
Swiss-prot Accession number	P01322 (Sequence in FASTA format)
Description	Insulin-1 precursor [Contains: Insulin-1 B chain; Insulin-1 A chain].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length	110 Amino acids
Molecular weight	12421
References	1  PubMed abstract 498283 2  PubMed abstract 498284 3  PubMed abstract 6249167 4  PubMed abstract 4311938 5  PubMed abstract 4640931 6  PubMed abstract 4554104
Domain Name	Insulin
Hormone Name	Insulin-1 A chain
Mature Hormone Sequence	GIVDQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein	21 Residues from position (90-110)
Receptor	P15127    Detail in HMRbase
Gene ID	24505
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	11403
Swiss-prot Accession number	P12706 (Sequence in FASTA format)
Description	Insulin-1 precursor [Contains: Insulin-1 B chain; Insulin-1 A chain].
Source organism	Xenopus laevis (African clawed frog)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the insulin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length	106 Amino acids
Molecular weight	12170
References	1  PubMed abstract 2722842 2  PubMed abstract 2661211
Domain Name	Insulin
Hormone Name	Insulin-1 A chain
Mature Hormone Sequence	GIVEQCCHSTCSLFQLESYCN
Position of mature hormone in Pre-Hormone protein	21 Residues from position (86-106)
Receptor	Q9PVZ4    Detail in HMRbase
Gene ID	378696
PDB ID	N/A
Drugpedia	wiki
Comments